fertility product reviews

Clomid-side effects,success rate


How does Clomifene work?

Length of treatment:

Who can use Clomifene?

Side Effects of Clomifene:

Success Rates of Clomifene:



One of the most well known and widely used fertility drugs – Clomifene – has helped many couples to solve their infertility issues. This wonderful drug helps women to increase their chances of ovulation every month. This is a well established line of treatment used by doctors to help women to conceive better. This drug is prescribed for all those women who have difficulty in ovulating – like those with Polycystic Ovarian Syndrome and unexplained infertility problems. With the use of Clomifene, they can help solve their ovulation troubles.

Clomid-side effects,success rate,cost

How does Clomifene work?

Clomifene acts more like a stimulator that helps your ovary perform ovulation at the proper time. The drug is available in a pill form for easy consumption. Clomifene’s important ingredient is Clomifene Citrate that is a kind of anti-oestrogen drug. When you take a dose of Clomifene, it leads to an increase in two hormones within your body. What this does is stimulate your ovaries to release an egg and thus help in ovulation in the normal way.

Clomifene sends signals to your pituitary gland to produce more of the hormones that actually trigger ovulation. In turn this leads to your ovaries getting your eggs lined up for ovulation and once it gets the signal from the brain, the ovaries send a mature egg from its follicle into the fallopian tubes helping it to meet the sperms. In other words, Clomifene helps in bringing around ovulation in the most natural way.

Length of treatment

Clomifene requires a long treatment period to help you to ovulate more regularly. Usually your doctor will monitor your progress using an ultrasound scan after the first cycle to see whether the drug is having the correct impact on you. You are required to start consuming these pills once you have passed through three to five days of your menstrual cycle. You then require continuing consuming them for five days in total. Ovulation will start around five to nine days after the last pill has been taken. At the time of ovulation, your ovaries will prepare the egg follicles and release the egg into the fallopian tube for fertilization.

Most doctors will prescribe you to go through a maximum of three to six drug cycles. However, for better results you can continue this course for twelve drug cycles taking a gap in between to help better ovulation and increases chances of your conception. For those who are suffering from Polycystic Ovarian Syndrome and have a Body Mass Index of more than 25, Clomifene will be prescribed by doctors only after they have lost some part of their weight. Even a five percentage drop in weight could bring in great results for such women. For such patients, doctors usually prescribe metformin tablets that are a kind of insulin-sensitizing drug. This pill will help your body to respond better to the treatment of Clomifene. In short, PCOS patients can use Metformin and Clomifene combination to help increase their chances of conception.

(Read more about Infertility Treatment)

Who can use Clomifene?

Apart from those suffering from lack of proper ovulation, Clomifene is usually prescribed for patients before they undergo IVF. This drug helps them to produce more eggs for the procedure and helps to boost the fertility treatment. Clomifene is also prescribed to men who suffer from sperm related problems due to hormonal imbalances. Thus, both men and women can use this drug.

Side Effects of Clomifene

Just like most other drugs, Clomifene has its own share of side effects. Some of the most visible side effects are:

Nausea and vomiting.

Tenderness feeling in the breasts.

Stomach pain.

Mood swings

Mild ovarian swelling.




Blurred vision.


Weight Gain.


Ovarian Cysts (in rare cases).

Dryness of Cervical Mucus causing pain during sexual intercourse.

Apart from all the above listed side effects, use of Clomifene on a regular basis for more than 12 cycles has been feared to lead to ovarian cancer. However, this is found to be more related with infertility rather than the use of this drug. Cases where such drug has been taken along with other fertility drugs like hmG have sometimes shown a tendency to develop Ovarian Hyperstimulation Syndrome. The patient might have a sudden weight gain and a bloated feeling as well. Only in some rare cases has this condition been found to be life threatening. The Ovarian Hyperstimulation Syndrome occurs when you react too well to the drug and produce too many eggs as well. On the other hand, some people have come to link miscarriages with the use of Clomifene. This is not true at all. There is very little evidence to prove this theory. If you want to improve fertility with no side effects, you can try some herb supplements.

Success Rates of Clomifene

The success rate of fertility drugs has been quite high as compared with other forms of infertility treatment. Also it helps you to avoid the painful consequences of surgery and becoming pregnant without much problem. In particular, patients using Clomifene drug have shown an increase in ovulation pattern by nearly 70%. Of those who have successfully ovulated using Clomifene, nearly 15-50% women have been able to conceive. The final figures depend upon various other related pregnancy factors.


Clomifene has helped scores of women to conceive and the only problem associated with the use of this drug might be the chances of you conceiving more than a single child in one delivery. This happens due to the increased number of eggs being released for fertilization. On the whole, Clomifene has shown quite good and positive results for its consumers and also has helped many infertile couples to conceive without resorting to surgery at all!

(Read more about Best reviewed fertility supplement)

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